SYNTHESIS OF ISOXAZOLYLPYRROLONES BY THREE-COMPONENT REACTION OF α-KETOGLUTARIC ACID OR ITS DIETHYL ESTER WITH 3-AMINO-5-METHYLISOXAZOLE AND AROMATIC ALDEHYDES

Авторы

  • Yana I. Sakhno Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
  • Oleksandr V. Radchenko Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
  • Elena A. Muravyova Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
  • Svitlana M. Sirko Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
  • Svitlana V. Shishkina Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
  • Vladimir I. Musatov Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine
  • Sergey M. Desenko Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine Faculty of Chemistry, V. N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv 61077, Ukraine
  • Valentyn A. Chebanov Division of Chemistry of Functional Materials, State Scientific Institution ''Institute for Single Crystals'' of National Academy of Sciences of Ukraine, 60 Nauky Ave., Kharkiv 61072, Ukraine Faculty of Chemistry, V. N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv 61077, Ukraine

DOI:

https://doi.org/10.1007/5942

Ключевые слова:

3-amino-5-methylisoxazole, α-ketoglutaric acid, [1-(5-methylisoxazol-3-yl)-5-oxo-2, 5-dihydro-1H-pyrrol-3-yl]acetic acid, multicomponent reaction.

Аннотация

[2-Aryl-4-hydroxy-1-(5-methylisoxazol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrol-3-yl]acetic acids and their esters were synthesized by the three-component reaction of α-ketoglutaric acid or its diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes.

Опубликован

2021-03-15

Выпуск

Раздел

Оригинальные статьи