SYNTHESIS OF 2-TRIAZOLYLPURINE PHOSPHONATES

Авторы

  • Zigfrīds Kapilinskis Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, 3 Paula Valdena St., Riga LV-1048, Latvia
  • Irina Novosjolova Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, 3 Paula Valdena St., Riga LV-1048, Latvia
  • Ērika Bizdēna Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, 3 Paula Valdena St., Riga LV-1048, Latvia
  • Māris Turks Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, 3 Paula Valdena St., Riga LV-1048, Latvia

DOI:

https://doi.org/10.1007/6037

Ключевые слова:

2, 6-bis(triazolyl)purines, purine phosphonates, 2-triazolylpurines, nucleophilic aromatic substitution.

Аннотация

A series of novel compounds containing triazole and phosphonate moieties were obtained under mild conditions. Reactions of 2,6-bis(triazolyl)purine acyclic nucleoside phosphonates, in which triazole ring at C-6 atom of purine was acting as a good leaving group, and N- or S-nucleophiles allowed to obtain the respective 2-triazolylpurine phosphonates in 62–87% yields.

Загрузки

Опубликован

2021-01-26

Выпуск

Том 57 № 1 (2021)

Раздел

Оригинальные статьи