IMIDAZOL-5-ONE-BASED DONOR–ACCEPTOR CYCLOPROPANES IN REACTION WITH C=S DIPOLAROPHILES

Авторы

  • Semen E. Nikolaev Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997
  • Anatolii I. Sokolov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997
  • Andrey A. Mikhaylov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997
  • Alexander A. Korlyukov Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997 A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28/1 Vavilova St., Moscow 119334
  • Nadezhda S. Baleeva Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997
  • Mikhail S. Baranov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997
  • Ivan N. Myasnyanko Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997

DOI:

https://doi.org/10.1007/7037

Ключевые слова:

donor–acceptor cyclopropanes, imidazolones, thioacetamide, thiophenes, thiourea

Аннотация

Interaction of imidazol-5-one-based donor–acceptor cyclopropanes with thiourea and thioacetamide was studied. Previously undescribed spirocyclic 2-amino- and 2-iminotetrahydrothiophenes are formed in the reaction.

Биографии авторов

Semen E. Nikolaev, Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997

1) Group of chemistry of heterocyclic compounds, undergraduate student

Anatolii I. Sokolov, Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997

1) Group of chemistry of heterocyclic compounds, Junior research fellow


2) Institute of Translational Medicine, Research Laboratory of Chemistry of Medicinal Substances, Junior research fellow

Andrey A. Mikhaylov, Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997

Group of chemistry of natural products, PhD, Senior research fellow

Nadezhda S. Baleeva, Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997

1) Group of chemistry of heterocyclic compounds, PhD, Junior research fellow


2) Institute of Translational Medicine, Research Laboratory of Chemistry of Medicinal Substances, PhD,, Junior research fellow

Mikhail S. Baranov, Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997

1) Group of chemistry of heterocyclic compounds, PhD, Senior research fellow, Head of laboratory


2) Institute of Translational Medicine, Research Laboratory of Chemistry of Medicinal Substances, PhD, Research fellow

Ivan N. Myasnyanko, Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovitianov St., Moscow 117997

1) Group of chemistry of heterocyclic compounds, PhD, Junior research fellow


2) Institute of Translational Medicine, Research Laboratory of Chemistry of Medicinal Substances, PhD, Head of laboratory

Загрузки

Опубликован

2022-12-20

Выпуск

Том 58 № 12 (2022)

Раздел

Оригинальные статьи