VISIBLE-LIGHT-INDUCED IR-CATALYZED SITE-SELECTIVE C−H TRIFLUOROMETHYLATION OF 3-SUBSTITUTED 1,2-BENZOXAZOLES

Ming-Ming Xiao; Ming-Qing Hua; Fang-You Mou; Heng-Ying Xiong

VISIBLE-LIGHT-INDUCED IR-CATALYZED SITE-SELECTIVE C−H TRIFLUOROMETHYLATION OF 3-SUBSTITUTED 1,2-BENZOXAZOLES

Авторы

Ming-Ming Xiao School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013
Ming-Qing Hua School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013
Fang-You Mou School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013
Heng-Ying Xiong College of Chemistry and Chemical Engineering, Henan University, Kaifeng Henan 475004

Ключевые слова:

trifluoromethyltion, visible-light photocatalysis, regioselectivity, 1,2-benzoxazoles

Аннотация

A new protocol for visible-light-induced C–H trifluoromethylation at C-4 position of 1,2-benzoxazoles has been disclosed with Togni reagent II at room temperature in the presence of fac-Ir(ppy)3. This approach features simple operation, high efficiency, and specific selectivity.