SYNTHESIS OF NEW ISOLATED AND FUSED TRI- AND TETRACYCLIC PYRIDINE DERIVATIVES

Авторы

  • F. A. El-Essawy Editorial Office "Chemistry of Heterocyclic Compounds"
  • W. A. El-Sayed National Research Centre
  • A. Sh. El-Etrawy College of Pharmacy, Misr University for Science and Technology
  • M. N. El-Bayaa Menoufia University

DOI:

https://doi.org/10.1007/863

Ключевые слова:

pyridine, tetrazole, thiazole, triazole, alkylation, cyclization, tetracyclic system

Аннотация

A number of functionalized pyridine derivatives in which the pyridine ring is linked to triazole, thiadiazole, thiazole and tetrazole moieties were synthesized by cyclization with carbon disulfide, phenylisothiocyanate, and sodium azide. Benzylation of the synthesized tetrazolylmethylpyridone derivative afforded the N(1)-benzylated product; its crystal structure was reported. The substituted fused tetracyclic pyridofuropyrimidine was synthesized by sequential reactions starting from the 2-pyridone derivative.

Also published in Chemistry of Heterocyclic Compounds, 2013, 48 (12), pp 1853-1862

http://link.springer.com/article/10.1007/s10593-013-1219-z

Биография автора

W. A. El-Sayed, National Research Centre

NBU University, Arar, Kingdom of Saudi Arabia

Загрузки

Опубликован

2013-08-21

Выпуск

Раздел

Оригинальные статьи