4-Hydroxy-2-quinolones. 26. Bromination of 3-substituted 2-oxo-4-hydroxyquinolones

Authors

  • И. B. Украинец Ukrainian Pharmaceutical Academy, Kharkov 310002
  • C. Г. Таран Ukrainian Pharmaceutical Academy, Kharkov 310002
  • O. А. Евтифеева Ukrainian Pharmaceutical Academy, Kharkov 310002
  • O. B. Гoроховa Ukrainian Pharmaceutical Academy, Kharkov 310002
  • Н. И. Филимонова Ukrainian Pharmaceutical Academy, Kharkov 310002
  • А. B. Туров Ukrainian Pharmaceutical Academy, Kharkov 310002

Abstract

The bromination of 3-alkyl- and 3-ethoxycarbonyl-2-oxo-4-hydroxyquinolones by molecular bromine gave 3-bromo-3-R-2,4-dioxoquinolones. Under analogues conditions, 1-R-2,4-dioxo-3H-quinolone-3-carboxylic acids form 1-R-3-bromo-2-oxo-4-hydroxyquinolones. The results of the study of the antimicrobial activity of the compounds synthesized are presented.

How to Cite
Ukrainets, I. V.; Taran, S. G.; Evtifeva, O. A.; Gorokhova, O. V.; Filimonova, N. I.; Turov, A. V Chem. Heterocycl. Compd. 1995, 31, 176. [Khim. Geterotsikl. Soedin. 1995, 204.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01169675

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Published

1995-02-25

Issue

No. 2 (1995)

Section

Original Papers