Halogenation of imidazo[4,5-<i>c</i>]pyridines

Authors

  • Ю. М. Ютилов L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk
  • И. А. Свертилова L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk

Abstract

Unsubstituted imidazo[4,5-c]pyridine does not react with chlorine, bromine, or iodine at room temperature or even upon heating to 160°C. The introduction of an oxo group activates the system such that halogenation proceeds readily. Imidazo[4, 5-c]pyridine gives 7-halo derivatives, while imidazo[4,5-c]pyridines give 4,7-dihalo products.

How to Cite
Yutilov, Yu. M.; Svertilova, I. A. Chem. Heterocycl. Compd. 1994, 30, 928. [Khim. Geterotsikl. Soedin. 1994, 1076.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165031

Downloads

Published

1994-08-25

Issue

No. 8 (1994)

Section

Original Papers