Pyrroloindoles. 15. Synthesis of tryptamine analogs. 6,7-dihydro-3-(2-phthalimidoethyl)-1H,5H-pyrrolo[2,3-<i>f</i>]indole and 3-(2-phthalimidoethyl)-1H,5H-pyrrolo[2,3-<i>f</i>]indole

Authors

  • Д. О. Kаджришвили Iv. Dzhavakhishvili Tbilisi, State University, Tbilisi 380028
  • E. H. Гордеев Iv. Dzhavakhishvili Tbilisi, State University, Tbilisi 380028
  • Ш. A. Самсония Iv. Dzhavakhishvili Tbilisi, State University, Tbilisi 380028
  • H. H. Суворов Iv. Dzhavakhishvili Tbilisi, State University, Tbilisi 380028

Abstract

Diazotization of 1-acetyl-5-aminoindoline and reaction of the diazonium salt with ethyl α-acetyl-δ-phthalimidovalerate gave the 1-acetyl-5-indolinyl hydrazone of ethyl α-keto-δ-phthalimidovalerate. Cyclization of the hydrazone and subsequent hydrolysis, decarboxylation, and dehydrogenation of the pyrroloindoline gave the corresponding tryptamines.

How to Cite
Kadzhrishvili, D. O.; Gordeev, E. N.; Samsoniya, S. A.; Suvorov, N. N. Chem. Heterocycl. Compd. 1994, 30, 188. [Khim. Geterotsikl. Soedin. 1994, 209.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165009

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Published

1994-02-25

Issue

No. 2 (1994)

Section

Original Papers