Cyclocondensation of 4-hydroxy-5,6-diaminopyrimidine with α,β-dihalochalcones

Authors

  • H. H. Колос Kharkov State University, Kharkov 310077
  • B. Д. Орлов Kharkov State University, Kharkov 310077
  • E. Ю. Юрьева Kharkov State University, Kharkov 310077
  • E. B. Жидкова Kharkov State University, Kharkov 310077

Abstract

The condensation of 4-hydroxy-5,6-diaminopyrimidine with 1,3-diaryl-2,3-dihalopropanones and with dibenzoylacetylenes was used to obtain derivatives of 1H-pyrimido[4,5-b]-1,5-diazepine and pyrimido[4,5-b]pyrazine, respectively. Their spectral characteristics were studied, and the directions in the formation of 7- and 6-membered heterocycles were determined. The synthesized pyrimido[4,5-b]pyrazines exist in the form of two tautomeric species — enaminocarbinol and enol forms, with an intramolecular hydrogen bond of the chelate type.

How to Cite
Kolos, N. N.; Orlov, V. D.; Yur'eva, E. Yu.;  Zhidkova, E. V Chem. Heterocycl. Compd. 1993, 29, 1210. [Khim. Geterotsikl. Soedin. 1993, 1409.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF00538070

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Published

1993-10-25

Issue

No. 10 (1993)

Section

Original Papers