REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-5-(INDOL-3-YL- AND -2-YL)PYRROLIDIN-2-ONES FROM AVAILABLE REAGENTS

Authors

  • А. В. Садовой M. V. Lomonosov State University, Moscow 119992
  • А. Э. Ковров M. V. Lomonosov State University, Moscow 119992
  • Г. А. Голубева M. V. Lomonosov State University, Moscow 119992
  • Л. А. Свиридова M. V. Lomonosov State University, Moscow 119992

DOI:

https://doi.org/10.1007/5249

Keywords:

1-alkyl-5-hydroxypyrrolidin-2-ones, 1-alkyl-5-indolylpyrrolidin-2-ones, indoles, amidoalkylation.

Abstract

The reaction under mild conditions of 1-alkyl-5-hydroxypyrrolidin-2-ones with different indoles having a free 3 position leads exclusively to 1-alkyl-5-(indol-3-yl)pyrrolidin-2-ones but if position 3 is occupied to 1-alkyl-5-(indol-2-yl)pyrrolidin-2-ones.

How to Cite
Sadovoy, A. V.; Kovrov, A. E.; Golubeva, G. A.; Sviridova, L. A.  Chem. Heterocycl. Compd. 2011, 46, 1215. [Khim. Geterotsikl. Soedin. 2010, 1505.]

For this article in the English edition see DOI 10.1007/s10593-011-0655-x



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Published

2019-07-08

Issue

No. 10 (2010)

Section

Original Papers