SYNTHESIS AND REACTIONS OF 1-R-3-BENZOYL-5-ETHOXYCARBONYL-6-OXO-1,2,3,6-TETRAHYDROPYRIDINE-2-THIONES

Authors

  • В. Н. Брицун Organic Chemistry Institute, National Academy of Sciences of Ukraine, Kiev 02660
  • А. Н. Есипенко Organic Chemistry Institute, National Academy of Sciences of Ukraine, Kiev 02660
  • А. Н. Чернега Organic Chemistry Institute, National Academy of Sciences of Ukraine, Kiev 02660
  • Э. Б. Русанов Organic Chemistry Institute, National Academy of Sciences of Ukraine, Kiev 02660
  • М. О. Лозинский Organic Chemistry Institute, National Academy of Sciences of Ukraine, Kiev 02660

DOI:

https://doi.org/10.1007/7339

Keywords:

1-R-3-benzoyl-5-ethoxycarbonyl-6-oxo-1, 2, 3, 6-tetrahydropyridine-2-thiones, diethyl ethoxymethylenemalonate, 6-ethoxycarbonyl-2-imino-8-methyl-4-phenyl-1, 7, 8-tetrahydropyrido[2, 3-d]-pyrimidin-7-one, 5-ethoxycarbonyl-7-methy-3-phenyl-6, 7-dihydroisoxazolo[3, 4-b]pyridine-6-one, N-R-3-oxo-3-phenylpropanethioamides, 9-R-7-ethoxycarbonyl-5-phenyl-8, 9-dihydropyrido[2, 3-d][1, 4]triazolo[1, 5-a]pyrimidin-8-ones, X-ray structural analysis, cycloacylation

Abstract

Cycloacylation of N-R-3-oxo-3-phenylpropanethioamides by diethyl ethoxymethylenemalonate occurs selectively to form 1-R-3-benzoyl-5-ethoxycarbonyl-6-oxo-1,2,3,6-tetrahydropyridine-2-thiones which are convenient starting materials for the synthesis of bi- and tricyclic hetero systems including the previously unknown 9-R-7-ethoxycarbonyl-5-phenyl-8,9-dihydropyrido[2,3-d][1,2,4]triazolo[1,5-a]-pyrimidin-8-ones.

How to Cite
Britsun, V. N.; Esipenko, A. N.; Chernega, A. N.; Rusanov, E. B.;  Lozinskii, M. O.  Chem. Heterocycl. Compd. 2007, 43, 1411. [Khim. Geterotsikl. Soedin. 2007, 1660.]

For this article in the English edition see DOI 10.1007/s10593-007-0218-3

 

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Published

2023-01-20

Issue

No. 11 (2007)

Section

Original Papers