A NOVEL SPIROHETEROCYCLIZATION: SYNTHESIS OF 1-ETHOXYCARBONYLMETHYLIDENE-8-(2'-ETHOXYCARBONYLMETHYLIDENE-5',5'-DIMETHYL-3'-PYRROLIDINYLIDENE)-3,3,6-TRIMETHYL-2-AZASPIRO[4,5]DECA-6,9-DIENE

Authors

  • Yu. V. Shklyaev Институт технической химии УрО РАН, Пермь 614990
  • Yu. V. Nifontov Institute of Technical Chemistry, Urals Branch of the Russian Academy of Sciences, Perm
  • M. I. Kodess Institute of Organic Synthesis, Urals Branch, Russian Academy of Sciences, Ekaterinburg
  • M. A. Ezhikova Institute of Organic Synthesis, Urals Branch, Russian Academy of Sciences, Ekaterinburg

DOI:

https://doi.org/10.1007/s10593-005-0056-0

Keywords:

isobutyraldehyde, meta-xylene, cyanoacetic ester, Ritter reaction, spiroheterocyclization

Abstract

It was shown that isobutyraldehyde and cyanoacetic ester enter into reaction with meta-xylene initially at the fourth carbon atom with the formation of a spiropyrroline ring and then at the newly formed exomethylene bond with closure of the 1-ethoxycarbonylmethylidene-8-(2'-ethoxycarbonylmethylidene-5',5'-dimethyl-3'-pyrrolidinylidene)-3,3,6-trimethyl-2-azaspiro[4,5]deca-6,9-diene system.

How to Cite
Shklyaev, Yu. V.;  Nifontov, Yu. V.; Kodess, M. I.; Ezhikova, M. A. Chem. Heterocycl. Compd. 2004, 40, 1283. [Khim. Geterotsikl. Soedin. 2004, 1487.]

 

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Published

2004-10-25

Issue

No. 10 (2004)

Section

Original Papers