HALOGEN-CONTAINING PYRIDINES. 8. SYNTHESIS OF 3,5-DICHLOROPYRIDINES CONTAINING PYRAZOLE AND PYRAZOLINE RESIDUES IN POSITION 2
Keywords:
halopyridines, N-substituted hydrazones, ∆2 -pyrazolines, pyrazolones, pyrazoles, pyridylhydrazines, condensationAbstract
The interaction of 3,5-dichloro-2-pyridylhydrazine with α,β-unsaturated carbonyl compounds leads to 1-(3,5-dichloro-2-pyridyl)-3,5-disubstituted ∆2-pyrazolines. It was shown that N-(3,5-dichloro-2-pyridyl)hydrazones of the corresponding aldehydes and ketones are formed as intermediates. Condensation of the hydrazine mentioned above with α,β-diketones gives 1,3,5-trisubstituted pyrazoles, but with acetoacetic ester a 1,3-disubstituted pyrazol-5-one containing a 3,5-dichloropyridyl residue is obtained.
How to Cite
Kobrakov, K. I.; Rybina, I. I.; Kelarev, V. I.; Korolev, V. K. Chem. Heterocycl. Compd. 2003, 39, 749. [Khim. Geterotsikl. Soedin. 2003, 877.]
For this article in the English edition, see DOI https://doi.org/10.1023/A:1025643011896
